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Researchers at National Jewish Health and partner institutions have discovered specific changes in immune cells in the lungs of people with sarcoidosis.

Antisense oligonucleotides (ASOs) have been proposed as a therapeutic approach to shut down the production of faulty proteins in a wide variety of diseases, including cancer. In a study published in the Journal of Cell Biology (JCB), researchers at the Cancer Research UK Scotland

The brain's immune cells are increasingly recognized as key players in Alzheimer's disease, but exactly how they change as the disease develops has remained unclear. A new study published in Nature Genetics provides the most comprehensive map to date of these cells, identifying a

A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow of patients with multiple myeloma and acute myeloid leukemia. The w

Researchers at the University of Colorado Anschutz Cancer Center have identified a previously unknown metabolic weakness in the stem cells that drive high-risk myelodysplastic syndromes (MDS), a discovery that could lead to more targeted treatments for this aggressive blood cance

A tumor is more than its cancer cells. Immune cells, blood vessels and other surrounding tissue influence how a cancer grows and responds to treatment. Two tumors containing the same cell types can respond very differently to the same therapy depending on how those cells are arra

Photosynthetic microorganisms can use light energy to convert carbon dioxide into useful compounds under mild, environmentally compatible conditions. However, many current photosynthetic production systems rely on cells growing freely in large volumes of liquid. This creates a su

Researchers at Tel Aviv University have developed a new method for diagnosing lung cancer: a simple, fast, low-cost blood test that does not require DNA sequencing. The method identifies a chemical fingerprint of cancer cells in the blood by analyzing cell-free DNA originating fr

Three research teams working independently around the world have landed on the same discovery: A single molecular "handshake" inside our cells controls a family of inflammatory diseases, including one of the most common inherited fevers on Earth. The finding solved a decades-old

The high cost of platinum is one of the main barriers to the wider adoption of hydrogen fuel cells. Now, researchers at IMDEA Materials Institute have developed a catalyst that delivers the same performance while using 75% less of this expensive metal. The study, published in Ele

Northwestern Medicine scientists have uncovered how a major Parkinson's disease gene disrupts the brain's most vulnerable dopamine-producing neurons before detectable neuronal loss. The study offers new clues for developing treatments that target the disease in its earliest stage

Parkinson's disease affects more than 10 million people worldwide. The disease is characterized by the buildup of abnormal clumps of the protein alpha-synuclein inside brain cells, but scientists have long struggled to understand exactly how these toxic forms of the protein cause